Transposition of the great arteries statpearls ncbi bookshelf. A report from the american society of echocardiography developed in collaboration with the society for cardiovascular magnetic resonance and the society of cardiovascular computed tomography. Transposition of the great arteries tga is a complex congenital heart defect. Transposition of the great arteries is a serious birth defect in which 2 large blood vessels leaving the heart are switched. Transposition of the great arteries 0 university of chicago. Many patients with ventriculoarterial discordance have survived to adulthood.
Transposition of the great arteries tga is a cyanotic congenital heart defect in which the aorta arises from the right ventricle and the pulmonary artery arises. Early surgery is essential and involves the arterial switch operation, which is carried out in the first week or two of life and corrects the abnormality. A heart in which the two main arteries carrying blood away from the heart are reversed. Complete transposition of the great arteries is also known as dtga. In children with tga, these arteries are connected to the heart abnormally. Pdf transposition of the great arteries researchgate. Many infants undergo a procedure in the catheterization laboratory to buy time and delay the surgery until they can handle it. Transposition of the great arteries cs mott childrens. Transposition of the great arteries tga is a pediatric cardiac congenital defect arising from an embryological discordance between the aorta.
Multimodality imaging guidelines of patients with transposition of the great arteries. Transposition of the great arteries tga is a congenital heart defect withventriculoarterialdiscordance in which the aorta is aligned with therightventricleandthepulmonary artery is aligned with the left ventricle. Clinical recognition can be challenging, so echocardiography is often the means by which definitive diagnosis is made. Aortic atresia with transposition of the great arteries. Transposition of the great arteries is a prevalent congenital heart defect with a high survival rate and a good longterm outcome, especially if managed with early surgical intervention during the neonatal period. Transposition of the great arteries or vessels tga tgv what is transposition of the great arteries vessels. In babies with this birth defect, the pulmonary artery and aorta are reversed. More information for parents of children with dtransposition what about surgical treatment. Corrected transposition of the great arteries is one of the most fascinating entities in congenital heart disease. In rare cases, even the chambers of the heart will be swapped.
To the best of our knowledge, no such case has been previously reported. The morphological right ventricle rv supports the systemic circulation and the morphological tricuspid valve is the systemic atrioventricular valve savv 1. The aorta typically carries oxygenrich blood to the body, while the pulmonary artery typically carries oxygen poor blood to the lungs. Multimodality imaging guidelines of patients with transposition of. Transposition of the great arteries tga is a cyanotic congenital heart defect in which the aorta arises from the right ventricle and the pulmonary artery arises from the left ventricle, creating two parallel circuits. To determine the relative position of the aorta and pulmonary artery in conventional chest roentgenograms, a correlative study with large roll film angiocardiograms was made in 70 cases of transposition of the great arteries, including 14 cases of double. We describe a rare case of newborn with aortic atresia and transposition of the great arteries who underwent successful surgical repair. Transposition of the great arteries tga, also referred to as complete transposition, is a congenital cardiac malformation characterised by atrioventricular concordance and ventriculoarterial va. We demonstrated that, even with a complex diagnosis, the patient could survive after rapid twostage norwood procedure.
Transposition of the great arteries vessels transposition of the great arteries, or tga, is a rare congenital heart defect the baby is born with it in which the two main arteries carrying blood out of the heart are switched in position. Pdf transposition of the great arteries tga, also referred to as complete transposition, is a congenital cardiac malformation characterised by. The two major arteries that carry blood away from the heart the aorta and the pulmonary artery are switched transposed. Methods in 76 adult patients with tga 59% male after atrial correction, longterm survival and morbidity were investigated in three periods. Contemporary management and outcomes in congenitally. When a dtransposition occurs, the blood pathway is impaired because the two arteries are connecting to the wrong chambers in the heart. Without an adequate supply of oxygenrich blood, the body cant function properly and your child faces serious complications or death without treatment. The switch means that the aorta, which normally carries oxygenated blood, carries deoxygenated blood. Transposition of the great arteries changes the way blood circulates through the body, leaving a shortage of oxygen in blood flowing from the heart to the rest of the body. Congenitally corrected transposition of the great arteries. Transposition of the great arteries tga is a group of congenital defects in which the position of major blood vessels of the heart are switched.
Normally, there are two separate blood vessels leaving the heart. In a normal heart, there are two large arteries that carry blood out of the heart. When atrioventricular av concordance is present, this anatomy results in cyanosis because the systemic and pulmo. Transposition of great arteries pronounced transpohzishun is a birth defect of the heart. Patients with transposition of the great arteries require surgery early in life to survive.
Complete transposition of the great arteries toga occurs when the aorta, which normally comes off the left ventricle and pumps red blood to the body, arises from the right ventricle1 and pumps blue blood returning from the body back to the body bypassing the lungs completely. From the division of cardiovascular diseases and department of internal medicine, mayo clinic, rochester, minn. Congenital heart disease, transposition of the great arteries, arterial switch operation, atrial switch. Objective this study assessed adult survival and morbidity patterns in patients who underwent atrial correction according to mustard or senning for transposition of the great arteries tga. Corrected transposition of the great arteries anmm. In a structurally normal heart, the aorta arises from the left ventricle and the pulmonary artery pa arises from the. In congenitally corrected transposition of the great arteries cctga, atrioventricular and ventriculoarterial discordance maintains the appropriate direction of blood. Tga causes the diversion of normal blood circulation, robbing the body of oxygen and nutrients. Over time, most patients develop systemic heart failure, even in the absence of associated lesions. Transposition of the great arteries or vessels tga tgv.
The aorta also tends to be on the right and anterior, and the great arteries are parallel rather than crossing as they do in the normal heart. Caudle, daniella transposition of the great arteries or tga is a potentially fatal congenital heart malformation where the pulmonary artery and the aorta are switched. The small coronary arteries, which feed the heart muscle with blood, need to be transferred as well as the two great arteries aorta and pulmonary artery. Complete transposition of the great arteries is a congenital cardiac anomaly in which the aorta arises from the morphological right ventricle, and the pulmonary. Characteristics and outcomes of transposition of great. Transposition of the great arteries tga, also referred to as complete transposition, is a congenital cardiac malformation characterised by atrioventricular concordance and ventriculoarterial va discordance. The pulmonary artery leaves the left ventricle, and the aorta leaves the right ventricle. Transposition of the great vessels is a type of congenital heart defect involving an abnormal arrangement of any of the great vessels such as the superior vena cava, pulmonary arteries and aorta. Transposition of the great arteries symptoms and causes. Transposition of the great arteries childrens hospital. Transposition of the great arteries tga is a heart defect that occurs from birth.
Transposition of the great arteries description and epidemiology. Congenital heart diseases concerning the primary arteries are further divided into subgroup called transposition of great arteries. Those with complete transposition of the great arteries have often had an atrial switch procedure mustard or. Babies with tga may need surgery or other procedures soon after.
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